KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKG
All Species:
21.82
Human Site:
Y424
Identified Species:
40
UniProt:
P49619
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49619
NP_001074213.1
791
89096
Y424
K
G
E
L
V
M
Q
Y
K
I
I
P
T
P
G
Chimpanzee
Pan troglodytes
XP_001152821
791
89168
Y424
K
G
E
L
V
M
Q
Y
K
I
I
P
T
P
G
Rhesus Macaque
Macaca mulatta
XP_001092912
791
89195
Y424
R
G
K
L
P
F
K
Y
K
I
I
P
T
P
G
Dog
Lupus familis
XP_545239
790
88986
Y423
K
G
E
L
V
M
Q
Y
K
I
I
P
T
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91WG7
788
88505
Y421
K
G
E
L
V
T
Q
Y
K
I
I
P
S
P
G
Rat
Rattus norvegicus
P49620
788
88503
Y421
K
G
E
L
V
M
Q
Y
K
I
I
P
S
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511802
697
78726
P371
K
F
Q
Y
L
L
N
P
R
Q
V
Y
S
L
S
Chicken
Gallus gallus
XP_422650
933
102351
R529
E
R
Q
S
H
C
R
R
S
D
S
E
S
P
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696120
893
99287
P502
E
S
S
P
S
T
S
P
E
D
T
G
Q
C
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
Q542
H
H
Q
A
T
H
F
Q
I
T
P
P
D
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
Q417
S
H
S
A
S
L
L
Q
A
V
S
P
S
N
D
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
T826
S
N
R
R
S
T
L
T
P
K
D
S
N
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
V402
S
S
V
Q
G
P
E
V
G
L
F
L
F
R
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.8
94
N.A.
89.7
88.2
N.A.
51.3
54.9
N.A.
59.2
N.A.
35.5
N.A.
46
38.3
Protein Similarity:
100
99.7
97.8
95.5
N.A.
94.1
93
N.A.
63.5
65.9
N.A.
72.7
N.A.
46.5
N.A.
63.2
48.8
P-Site Identity:
100
100
66.6
100
N.A.
86.6
93.3
N.A.
6.6
6.6
N.A.
0
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
86.6
100
N.A.
93.3
100
N.A.
46.6
33.3
N.A.
13.3
N.A.
13.3
N.A.
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
16
0
0
0
0
8
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
16
8
0
8
0
8
% D
% Glu:
16
0
39
0
0
0
8
0
8
0
0
8
0
8
0
% E
% Phe:
0
8
0
0
0
8
8
0
0
0
8
0
8
0
8
% F
% Gly:
0
47
0
0
8
0
0
0
8
0
0
8
0
0
47
% G
% His:
8
16
0
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
47
47
0
0
0
0
% I
% Lys:
47
0
8
0
0
0
8
0
47
8
0
0
0
0
8
% K
% Leu:
0
0
0
47
8
16
16
0
0
8
0
8
0
8
8
% L
% Met:
0
0
0
0
0
31
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
8
0
0
0
0
0
8
8
0
% N
% Pro:
0
0
0
8
8
8
0
16
8
0
8
62
0
54
0
% P
% Gln:
0
0
24
8
0
0
39
16
0
8
0
0
8
0
0
% Q
% Arg:
8
8
8
8
0
0
8
8
8
0
0
0
0
8
0
% R
% Ser:
24
16
16
8
24
0
8
0
8
0
16
8
39
0
16
% S
% Thr:
0
0
0
0
8
24
0
8
0
8
8
0
31
0
0
% T
% Val:
0
0
8
0
39
0
0
8
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
47
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _